Sodium Hyaluronate

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Sodium Hyaluronate

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What is Sodium Hyaluronate (Hyaluronic Acid)?

Sodium hyaluronate is the salt form of hyaluronic acid. Hyaluronic acid powder is also named hyaluronan powder. It is an anionic, nonsulfated glycosaminoglycan, naturally present in the human body. It is found in the highest concentrations in fluids in the eyes and joints. It's molecular weight is from several ten thousand to several million. It's aqueous solution has outstanding moisture keeping ability, high viscoelasticity and lubricity.

It is commonly a sodium salt, called sodium hyaluronate, habitually called hyaluronic acidHyaluronic Acid(Sodium Hyaluronate). Hyaluronic Acid(Sodium Hyaluronate) is a new biological at home and abroad. Its molecular weight is from several ten thousand to several million. It's aqueous solution has outstanding moisture keeping ability, high viscoelasticity and lubricity. It is widely used in cosmetics, pharmacy and health and beauty food.

Specifications:

ITEMS	STANDARD
Description	White Powder
PH (0.1% water solution)	6.0~7.5
Glucuronic acid	42.0% min.
Sodium Hyaluronate	91.0% min.
Molecular weight,Da	0.80~1.20×106min
Transparency (in 0.1% aq.sol.)	98.5% min.
Protein	0.1% max.
Loss on drying	10.0% max.
Residue on ignition	20.0% max.
Mesh size	95%min pass 80mesh
Bulk density (g/ml)	---
Heavy metals	20ppm max.
Lead	3.0ppm max.
Cadmium	1.0ppm max.
	0.1ppm max.
Arsenic	1.0ppm max.
Pesticides	0.01 mg/kg max.
Total plate count	10000cfu/g max.
Yeast/moulds count	1000cfu/g max.
Escherichia coli	Negative
Salmonella	Negative
Irradiation status	Non irradiated

We have different molecular weight Hyaluronic acid
Type	Molecular weight	Effects	Application
High Molecular weight	>1600kDa	Moisturizing and lubricating; good repairing effect	Recommend Molecular weight Tablet, capsules(800kDa-1200KDa) Solution, Sofegel(Less than 300kDa) Cream Eye cream(1000KDa-1300kDa) Facial cleanser, lotion,essence(800KDa-1000Kda) Mask(1300-1500KDa) Other Molecular weight can also be used, low molecular weight is more easily absorbed, high Molecular weight can lock the moisture easily, they can be combined and used together.
Medium Molecular weight	200 kDa~1600 kDa	Moisturizing,Diluting,releasing,stabilizing and emulsifying effect
Low Molecular weight	10 kDa ~200 kDa	Nourishing the skin and Long-lasting moisturizing
Ultra-low Molecular weight	<10 kDa	Transdermal absorption, deep hydration, anti-aging, repair after sun exposure

Product Application

1. Food Industry.

Hyaluronic Acid(Sodium Hyaluronate) can be added into drinks, mink products, health care capsules, etc.

2. Cosmetic Industry

(1) <10,000Da (Super Low Molecular Weight):

Making Hyaluronic Acid(Sodium Hyaluronate) smaller means it can reach a bit farther into skin's uppermost layers for visibly enhanced results, so it has the best effect of moisturzing and anti-aging.

(2) 10,000Da-200,000Da (Low Molecular Weight)

Hyaluronic Acid(Sodium Hyaluronate) has better moisture effect than regular molecular weight.

(3) 200,000Da-1,600,000Da (Regular Molecular Weight)

Hyaluronic Acid(Sodium Hyaluronate) can retain moisture, keep the skin firm, and prevent wrinkles by adding volume to the skin.

(4) >1,600,000Da (High Molecular Weight)

Hyaluronic Acid(Sodium Hyaluronate) can keep moisturing for longer time, and repair skins.

3. Eyedrop Industry

Hyaluronic Acid(Sodium Hyaluronate)can be used in eye surgeries including cataract removal, corneal transplantation, and repair of a detached retina and other eye injuries.

4. Injection Industry

Hyaluronic Acid(Sodium Hyaluronate) can be made into Hyaluronic Acid(Sodium Hyaluronate) filler used on our body, like face, lip, breast, etc.

Functions and Application of Hyaluronic acid
Grade	Functions	Application
Food grade	Restore skin moisture, improve skin health condition; Antioxidation; Improve joint health; Improve bowel function and protect gastric mucosa.	Common food: beverage, jelly, dairy products etc., Healthy food: usually in combination with Collagen, Vitamins, Chondroitin Sulphate, to make tablets, capsules or oral liquid.
Cosmetic Grade	Lubricating and film-forming, moisturizing, preventing skin damage, thickening and keeping emulsion stable; Nourishing the skin, long-lasting moisturizing; Trans-dermal absorption, deep hydrating, anti-ageing, repairing skin damage.	Skin care products:cream, emulsion, essence, lotion, gel, facial mask, etc.; Beauty products: lipstick, eye shadow, foundation, etc.; Cleansing products: facial cleanser, body wash, etc.; Hair products: shampoo, hair conditioner, styling gel, hair restorer, etc.
Eye Drop Grade	Lubricating, moisturizing, improving efficacy of drugs, relieving dry eye syndrome, and promote healing of corneal and conjunctiva injury; Wound healing; Repairing damaged mucous membrane or cartilage, etc.	For parenteral preparations or oral preparations not including intra-articular and intra-ocular preparations. It can be used in eye drops, contact lens solutions, topical preparations for wound or burn healing, medical lubricants etc.
Injection Grade	Protecting corneal endothelium; Lubricating, repairing damage cartilage, inhibition of inflammation;	For parenteral preparations including intra-articular and intra-ocular preparations, such as intra-articular injections, intradermal injections for aesthetic correction, anti-adhesive products, etc.

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